A constituent unit of Shri Dharmasthala Manjunatheshwara University
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Assistant Professor
| Dr. Jagadeesha Poyya is Assistant Professor at the SDM Research Institute for Biomedical Sciences, Shri Dharmasthala Manjunatheshwara University, Dharwad. He specializes in the study of the PHD2/HIF-1α signaling pathway in ischemic and cancer diseases, with a strong interest in cancer epigenetics. His expertise spans computational biology, molecular modeling, small molecule optimization, and omics-based research, supported by high-performance computing. He holds a Ph.D. in Biochemistry with research focused on hypoxia regulation, and continues to contribute to translational approaches aimed at developing targeted therapies while actively engaging in teaching, mentoring, and collaborative research. |
Ph.D. Scholar/Projects Fellows/Trainees
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| He brings a wealth of experience to his professional journey, having worked in various roles within the field of biomedicine & computational biology. Notably, he served as a project assistant at the Central University of Hyderabad, Telangana, where he actively contributed to research projects & collaborated with a diverse team |
| In addition, he served as the Journal Manager of Biomedicine, the official publication of the Indian Association of Biomedical Scientists (IABMS). In this role, he demonstrated his organizational & management skills by overseeing the publication process & ensuring the smooth functioning of the journal & indexing. The Biomedicine journal, with its print ISSN of 0970 2067, serves as a platform for disseminating cutting-edge research in the field. |
| Furthermore, he took on the responsibility of being the Web Manager for the Indian Association of Biomedical Scientists (IABMS), where he utilized his technical expertise to maintain & optimize the association's website (https://iabms.in). His contribution ensured a user-friendly & informative online presence for the association. Also, part of technical team in various annual conferences conducted by IABMS. |
| He has established himself as an expert in computational biology, with a strong foundation in lead discovery, small molecule optimization, preclinical evaluation, molecular modeling, system biology, & pharmacokinetics. His diverse skillset enables him to tackle challenging research problems & make valuable contributions to the advancement of scientific knowledge. |
| He is a highly accomplished researcher in the field of Biochemistry, he conducted a noteworthy research project during master degree dissertation, where he focused on isolating Serine Protease Inhibitors from Guizotia abyssinica (NIGER) Seeds. This research showcased his expertise & dedication to exploring novel biochemical compounds. |
| Continuing his academic journey, he pursued a Ph.D in Biochemistry. His doctoral research revolved around evaluating the inhibition of the Hypoxia inducible factor-1α-β protein heterodimerization using LMCs as lead molecules. This particular study reflects his keen interest in understanding protein interactions & their implications in cellular processes. |
| Furthermore, he has made valuable contributions to various research projects during his academic career. He conducted computational studies & performed data representation for several investigations. Notable among these studies were the screening of natural plant compounds as potential inhibitors for Protein Arginine Methyltransferase-5, molecular phylogenetic evaluation of endophytic fungi isolated from Tragia involucrata Linn. |
| With a strong foundation in Biochemistry & a diverse range of research experiences, he has demonstrated his ability to contribute valuable insights & findings to the scientific community. His expertise in computational studies, data analysis, & in-vitro experimental techniques makes him a valuable asset to any research team. |
| Kulkarni A, Kulkarni CC, Pradeep SR, Poyya J, et al (2025) Role of Anti-Inflammatory and Antioxidant Properties of Natural Products in Curing Cardiovascular Diseases. CIMB 47:955. https://doi.org/10.3390/cimb47110955 |
| Nalla K, Chatterjee B, Poyya J, et al (2025) Ellagic Acid Inhibits EZH2: A Potential Epigenetic Therapeutic Molecule for Cancer. Cancer Genetics S2210776225001115. https://doi.org/10.1016/j.cancergen.2025.09.001 |
| Padakannaya A, Poyya J, Patel JIA, Kurdekar NM, Khandagale AS. Computational discovery of potential human carbonic anhydrase IX inhibitors. Journal of Biomolecular Structure and Dynamics 2025:1–13. https://doi.org/10.1080/07391102.2025.2472395 |
| Patel JIA, Poyya J, Padakannaya A, Kurdekar NM, Khandagale AS, Joshi CG, et al. Mechanistic insights into gut microbe derived siderophores and PHD2 interactions with implications for HIF-1α stabilization. Scientific Reports 2025;15:1113. https://doi.org/10.1038/s41598-024-83730-8 |
| Nalla K, Chatterjee B, Poyya J, Swain A, Ghosh K, Pan A, et al. Epigallocatechin-3-gallate inhibit the protein arginine methyltransferase 5 and enhancer of Zeste homolog 2 in breast cancer both in vitro and in vivo. Archives of Biochemistry and Biophysics 2025;763:110223. https://doi.org/10.1016/j.abb.2024.110223 |
| Dinesh B, Poyya J, Zameer F, Sannegowda LK, Joshi CG, Raghu AV. Effect of Polyvinylpyrrolidone on Antioxidant and Antibacterial Activity of Silver Metal Nanoparticles: A Comparative Analysis. Proc Natl Acad Sci, India, Sect A Phys Sci 2024;94:359–68. https://doi.org/10.1007/s40010-024-00882-y |
| Kumar K, Badni M, AS S, Poyya J, Hallikeri K, Oli AK. Long noncoding RNA hot air an independent predictive marker of overall survival and loco-regional recurrence in oral squamous cell Carcinoma. Onkologia i Radioterapia 2024;18. |
| Poyya J, Danagoudar A, Joshi CG, Khandagale AS, Narayanappa Govinda R. Computational Investigation of Endophytic Fungal (Penicillium citrinumCGJ-C2) Compound and Its In-silico Derivatives for the Inhibition ofRNA-Dependent RNA Polymerase of SARS-CoV-2. COVID 2023;4:e161023222258. https://doi.org/10.2174/0126667975260543231011113718 |
| Ali A, Wani AB, Malla BA, Poyya J, Dar NJ, Ali F, et al. Network Pharmacology Integrated Molecular Docking and Dynamics to Elucidate Saffron Compounds Targeting Human COX-2 Protein. Medicina 2023;59:2058. https://doi.org/10.3390/medicina59122058 |
| Kumar K, Hallikeri K, Oli A, Goni M, Jain A, Poyya J, et al. Quantitative Analysis of lncRNA in Formalin-fixed Paraffin-embedded Tissues of Oral Squamous Cell Carcinoma. BioTechniques 2023;75:133–42. https://doi.org/10.2144/btn-2023-0033 |
| Dinesh B, Monisha N, Shalini HR, Prathap GK, Poyya J, Shantaram M, et al. Antibacterial activity of silver nanoparticles synthesized using endophytic fungus— Penicillium cinnamopurpureum. Spectroscopy Letters 2022;55:20–34. https://doi.org/10.1080/00387010.2021.2010764 |
| Journal Manager of Biomedicine (Print ISSN: 0970 2067), official publication of Indian Association of Biomedical Scientists (IABMS)(https://biomedicineonline.org). |
| Web Manager of Indian Association of Biomedical Scientists (IABMS)(https://iabms.in) |