A constituent unit of Shri Dharmasthala Manjunatheshwara University
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Director (Research)
| Dr. K. Satyamoorthy holds the administrative & research position at Shri Dharmasthala Manjunatheshwara (SDM) University tasked to elevate national & international interdisciplinary research endeavours, inculcate translational research at the grassroot level & promote innovation & entrepreneurship. |
| Over the years, Dr. Satyamoorthy is credited with building research & innovation Institutions of repute & partake in number of research & academic excellence endeavours. His research team undertakes interrogation of genetic & epigenetic mechanisms for diagnosis, prognosis & treatment of selected communicable & non-communicable disorders. |
| He & his team has been credited with over 340 publications, several patents, & applications; & he has been the recipient of several awards. Dr Satyamoorthy has successfully collaborated with national & international academia & industry researchers. |
Ph.D. Scholar/Projects Fellows/Trainees
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| 2025 |
| Patel, JIA, Poyya J, Padakannaya, NM Kurdekar, AS Khandagale et al. "Mechanistic insights into gut microbe derived siderophores and PHD2 interactions with implications for HIF-1α stabilization." Scientific Reports 15.1 (2025): 1113. |
| Prasad, Keshava, et al. "Promotion of cellular differentiation and DNA repair potential in brain cancer cells by Shankhpushpi,(Clitoria ternatea L.) with rasayana properties in vitro." Journal of Ayurveda and Integrative Medicine 16.1 (2025): 101050. |
| Mukundan, Nidhi S., Kapaettu Satyamoorthy, and Vidhu Sankar Babu. "Advancing plant protoplasts: innovative techniques and future prospects." Plant Biotechnology Reports (2025): 1-20. |
| Warrier A, Satyamoorthy K, Murali TS (2025). Naringenin as a Potent Natural Biofilm Inhibitor of Pseudomonas aeruginosa in Diabetic Foot Ulcers Through lasR Competitive Inhibition. Current Microbiology 82 (7), 1-18, 2025. |
| George N, Fernandes R, Satyamoorthy K (2025). ARID1A-driven modulation of EZH2 impedes proliferation and enhances senescence in breast cancer cells. Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms, 195102, 2025. |
| S Upadhya, MJ Andrade, V Shukla, R Rao, K Satyamoorthy (2025). Genetic and immune dysregulation in vitiligo: Insights into autoimmune mechanisms and disease pathogenesis. Autoimmunity Reviews, 103841, 2025. |
| Poojary G, Vasishta S, Thomas RH, Satyamoorthy K, Padmakumar R, et al. (2025). Exercise improves systemic metabolism in a monocrotaline model of pulmonary hypertension. Sports Medicine and Health Science 7 (1), 37-47, 2025. |
| Pai, P., et al. "32P Investigating the mechanistic pathways of a novel HDAC inhibitor in neuroblastoma." ESMO Open 10 (2025). |
| K Prasad, SC Kaul, R Wadhwa, KP Guruprasad, K Satyamoorthy (2025). Cellular oxidative stress and sirtuins mediate regulation of senescence and neuronal differentiation by withaferin A. Free Radical Biology and Medicine 233, 174-185, 2025. |
| P Pai, MG Shetty, K Satyamoorthy, BK Sundara (2025). 32P Investigating the mechanistic pathways of a novel HDAC inhibitor in neuroblastoma. ESMO Open 10, 2025. |
| 2024 |
| Chaudhari S, Acharya LP, Jasti DB, Ware AP, Gorthi SP, Satyamoorthy K. 2024. Discovery of a Novel Shared Variant Among RTEL1 Gene and RTEL1-TNFRSF6B lncRNA at Chromosome 20q13.33 in Familial Progressive Myoclonus Epilepsy. International Journal of Genomics, 7518528 doi: 10.1155/2024/7518528. |
| Ware AP, Satyamoorthy K, Paul B. 2024. CmirC update 2024: a multi-omics database for clustered miRNAs. Funct Integr Genomics. 2024 Aug 1;24(4):133. doi: 10.1007/s10142-024-01410-2. |
| Sachdeva C, Satyamoorthy K, Murali TS. 2024. Pseudomonas aeruginosa: metabolic allies and adversaries in the world of polymicrobial infections. Critical Reviews in Microbiology. August. https://doi.org/10.1080/1040841X.2024.2397359 |
| George N, Joshi MB, Satyamoorthy K. 2024. DNA damage-induced senescence is associated with metabolomic reprogramming in breast cancer cells. Biochimie. 216:71-82. |
| Mukundan NS, Satyamoorthy K, Babu VS. 2024. Investigating photosynthetic evolution and the feasibility of inducing C4 syndrome in C3 plants. Plant Biotech Rep., https://doi.org/10.1007/s11816-024-00908-2. |
| Prasad K, Saggam A, Guruprasad KP, Tillu G, Patwardhan B, Satyamoorthy K. 2024. Molecular mechanisms of Asparagus racemosus willd. and Withania somnifera (L.) Dunal as chemotherapeutic adjuvants for breast cancer treatment. J Ethnopharmacol., Apr 28:331:118261. doi: 10.1016/j.jep.2024 118261. |
| Shetty MG, Pai P, Dey B, Satyamoorthy K, Shil S, Nayak UY, T A, Sundara BK. 2024. Evaluation of 1,10-phenanthroline-based hydroxamate derivative as dual histone deacetylases/ribonucleotide reductase inhibitor with antitumor activities. Daru, 32(1):263-278. doi: 10.1007/s40199-024-00514-1. Epub 2024 Apr 29. |
| Shetty MG, Pai P, Padavu M, Satyamoorthy K, Kampa Sundara B. 2024. Synergistic therapeutics: Co-targeting histone deacetylases and ribonucleotide reductase for enhanced cancer treatment. Eur J Med Chem. 2024 Mar 16;269:116324. |
| Disha B, Mathew RP, Dalal AB, Mahato AK, Satyamoorthy K, Singh KK, Thangaraj K, Govindaraj P. 2024. Mitochondria in biology and medicine - 2023. Mitochondrion2024 May: 76:101853. doi: 10.1016/j.mito.2024.101853. |
| Edwin RK, Acharya LP, Maity SK, Chakrabarti P, Tantia O, Joshi MB, Satyamoorthy K, Parsa KVL, Misra P. 2024. TGS1/PIMT knockdown reduces lipid accumulation in adipocytes, limits body weight gain and promotes insulin sensitivity in mice. Biochim Biophys Acta Mol Basis Dis. 2024 Jan;1870(1):166896. doi: 10.1016/j.bbadis.2023.166896. Epub 2023 Sep 24. |
| Manzoor HB, Asare-Werehene M, Pereira SD, Satyamoorthy K, Tsang BK. 2024. The regulation of plasma gelsolin by DNA methylation in ovarian cancer chemo-resistance. J Ovarian Res 2024 Jan 12;17(1):15. doi: 10.1186/s13048-023-01332-w. |
| Gupta H, Sharma S, Gilyazova I, Satyamoorthy K. Molecular tools are crucial for malaria elimination. Mol Biol Rep., Apr 20;51(1):555. doi: 10.1007/s11033-024-09496-4. |
| Mukundan NS, Satyamoorthy K, Babu VS. 2024. Investigating photosynthetic evolution and the feasibility of inducing C4 syndrome in C3 plants. Plant Biotech Rep., https://doi.org/10.1007/s11816-024-00908-2. |
| Mukundan NS, Satyamoorthy K, Babu VS. 2024. Investigating photosynthetic evolution and the feasibility of inducing C4 syndrome in C3 plants. Plant Biotech Rep., https://doi.org/10.1007/s11816-024-00908-2. |
| Poojary G, Vasishta S, Thomas HR, Satyamoorthy K, Padmakumar R, Joshi MB, Babu AS. Exercise improves systemic metabolism in a monocrotaline model of pulmonary hypertension. Sports Med Health Sci 2024 [in press] |
| Disha B, Mathew RP, Dalal AB, Mahato AK, Satyamoorthy K, Singh KK, Thangaraj K, Govindaraj P. 2024. Mitochondria in biology and medicine - 2023. 2024. Mitochondrion. 2024 Feb 28;76:101853. |
| Prabhu, S.R., Ware, A.P., Satyamoorthy, K. et al. MicroRNA Guided In Silico Drug Repositioning for Malaria. Acta Parasit. (2024). https://doi.org/10.1007/s11686-024-00897-w |
| Sachdeva, C., Satyamoorthy, K., & Murali, T. S. (2024). Pseudomonas aeruginosa: metabolic allies and adversaries in the world of polymicrobial infections. Critical Reviews in Microbiology, 1–20. |
| 2023 |
| Chaudhari S, Ware AP, Jasti DB, Gorthi SP Acharya LP, Bhat M, Mallya M, Satyamoorthy K. 2023. Exome sequencing of choreoacanthocytosis reveals novel mutations in VPS13A and co-mutation in modifier gene(s). Mol Genet Genomics, 298(4):965-976. doi: 10.1007/s00438-023-02032-2. |
| Jnana A, a Sadiya SS, Satyamoorthy K, Murali TS. 2023. Extracellular vesicles in bacterial and fungal diseases – Pathogenesis to diagnostic biomarkers. Virulence. 14(1): 2180934. |
| Ghosh S, Kundu R, Chandana M, Das R, Anand A, Beura S, Bobde RC, Jain V, Prabhu SR, Behera PK, Mohanty AK, Chakrapani M, Satyamoorthy K, Suryawanshi AR, Dixit A, Padmanaban G, Nagaraj VA. 2023. Distinct evolution of type I glutamine synthetase in Plasmodium and its species-specific requirement. Nat Commun. 2023 Jul 14;14(1):4216. doi: 10.1038/s41467-023-39670-4. |
| Ware AP, Satyamoorthy K, and Paul B. 2023. Integrated multiomics analysis of chromosome 19 miRNA cluster in bladder cancer. Functional & Integrative Genomics (2023) 23:266. https://doi.org/10.1007/s10142-023-01191-0. |
| Nayak N, Satyamoorthy K, Sreepathy MT. 2023. Next-generation sequencing technology for the diagnosis of microbial infections in hard-to-heal wounds. J Wound Care, 2023 Jun 1;32(Sup6a):xcvii-cix. doi: 10.12968/ jowc.2023.32.Sup6a.xcvii. |
| Tanwar AS, Shruptha P, Jnana A, Brand A, Ballal M, Satyamoorthy K, Murali TS. 2023. Emerging Pathogens in Planetary Health and Lessons from Comparative Genome Analyses of Three Clostridia Species. OMICS. 2023 May 16. doi: 10.1089/omi.2023.0034. |
| Bhat S, Rotti H, Prasad K, Kabekkodu SP, Saadi AV, Shenoy SP, Joshi KS, Nesari TM, Shengule SA, Dedge AP, Gadgil MS, Dhumal VR, Salvi S, Satyamoorthy K. 2023. Genome-wide DNA methylation profiling after Ayurveda intervention to bronchial asthmatics identifies differential methylation in several transcription factors with immune process related function. Journal of Ayurveda and Integrative Medicine, 14, (2), 100692, https://doi.org/10.1016/j.jaim.2023.100692. |
| Prabhu SR, Ware AP, Umakanth S, Hande M, Mahabala C, Saadi AV, Satyamoorthy K. 2023. Erythrocyte miRNA-92a-3p interactions with PfEMP1 as determinants of clinical malaria. Functional and Integrative Genomics. 23(2):93. doi: 10.1007/s10142-023-01028-w. |
| Kabekkodu SP, Chakrabarty S, Jayaram P, Mallya S, Thangaraj K, Singh KK, Satyamoorthy K. 2023. Severe acute respiratory syndrome coronaviruses contributing to mitochondrial dysfunction: Implications for post-COVID complications. Mitochondrion. 69:43-56. doi: 10.1016/j.mito.2023.01.005. Epub 2023 Jan 20. |
| Tanwar AK, Padival S, Paul B, Murali TS, Brand A, and Satyamoorthy K. 2023. How Can Omics Inform Diabetic Foot Ulcer Clinical Management? A Whole Genome Comparison of Four Clinical Strains of Staphylococcus aureus. Omics. 27(2):51-61. doi: 10.1089/omi.2022.0184. Epub 2023 Feb 8. |
| Sharma R, Maity SK, Chakrabarti P, Katika MR, Satyamoorthy K, Kishore V. L Parsa, Misra P. (2023). PIMT controls insulin synthesis and secretion through PDX1. Int J Mol Sci (2023 May; 24(9): 8084). |
| George N, Bhandari P, Shruptha P, Jayaram P, Sima Chaudhari S, Satyamoorthy K. 2023. Multidimensional outlook on the pathophysiology of cervical cancer invasion and metastasis. Mol and Cell Biochem., 11:1-26. doi: 10.1007/s11010-023-04686-3. |
| Suresh Babu TV, Kabekkodu SP, Satyamoorthy K, Shantaram M. 2023. Molecular characterization and mutational analysis of β-globin gene among Kodagu population of Karnataka, India. Biomedicine, 43: 482-487. DOI: 10.51248/.v43i01.2686. |
| Divya M, Prabhu SR, Satyamoorthy K, Saadi AV. 2023. Therapeutics through glycobiology: an approach for targeted elimination of malaria. Biologia (Bratisl). 10;1-5. doi: 10.1007/s11756-023-01312-x. |
| Prabhu NB, Vasishta S, Bhat SK, Joshi MB, Kabekkodu SP, Satyamoorthy K, Rai PS. 2023. Distinct metabolic signatures in blood plasma of bisphenol A-exposed women with polycystic ovarian syndrome. Environ Sci Pollut Res Int., 2023 Apr 15. doi: 10.1007/s11356-023-26820-w. |
| Challa NL, Sarkar A, Satyamoorthy K, Phanithi PB, Chakrabarti P, Parsa KVL, Misra P. 2023. TGS1/PIMT regulates pro-inflammatory macrophage mediated paracrine insulin resistance: Crosstalk between macrophages and skeletal muscle cells. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1870, (1), 2024, 166878. |
| Kulala DS, Prasad K, Reddy PS, Maruthiyodan S, Joshi MB, Satyamoorthy K, Guruprasad KP. 2023. Understanding the effects of Abhraka Bhasma on genotoxicity and its DNA repair potential in mouse model. J Ayurveda Integr Med. 2023 Mar-Apr;14(2):100598. doi: 10.1016/j.jaim.2022.100598. |
| Mukundan NS, Banerjee S, Kumar S, Satyamoorthy K, Babu VS. C4 equivalent decarboxylation competence in tropical orchids. J Plant Biol., 2023, 66, 163-180. |
| Samantray D, Tanwar AS, Murali TS, Brand A, Satyamoorthy K, Paul B. 2023. A Comprehensive Bioinformatics Resource Guide for Genome-Based Antimicrobial Resistance Studies. OMICS. 2023 Oct;27(10):445-460. |